Figure 1.

Schematic review of different dimensions of kidney disease and health on the basis of biomarker profiles in DKD progression integrated into a unified multidimensional predictive model which ascertains patients at low risk, intermediate risk, and high risk. suPAR, soluble urokinase plasma activator receptor; KIM-1, kidney injury molecule-1; MCP-1, monocyte chemoattractant protein-1; MMP-7, matrix metallopeptidase 7; WFDC2, WAP four-disulfide core domain protein; UACR, urine albumin-creatinine ratio; AGP, axon guidance proteins; EFNA4, Ephrin ligand 4; EPHA2, Ephrin receptor 2.