Table II.

Illustrates the enriched gene ontology terms of the genes significantly higher expressed in the YMA MII compared with the AMA MII oocytes.

Gene ontology	Term	Count	%	P-value	FDR
BP	Mitochondrial respiratory chain complex I assembly	22	2.2	2.3E−13	4.0E−10
BP	Mitochondrial translational elongation	23	2.3	1.9E−11	3.3E−8
BP	Mitochondrial electron transport, NADH to ubiquinone	18	1.8	2.1E−11	3.8E−8
BP	Mitochondrial translational termination	22	2.2	1.8E−10	3.1E−7
BP	Translation	28	2.8	3.6E−5	6.4E−2
BP	ER to Golgi vesicle-mediated transport	20	2.0	1.2E−4	2.2E−1
Gene ontology	Term	Count	%	P-value	FDR
CC	Mitochondrial inner membrane	70	6.9	8.7E−20	1.3E−16
CC	Mitochondrion	130	12.8	4.2E−17	6.2E−14
CC	Mitochondrial large ribosomal subunit	19	1.9	1.1E−12	1.6E−9
CC	Mitochondrial respiratory chain complex I	18	1.8	2.1E−11	3.0E−8
CC	Extracellular exosome	194	19.1	6.6E−10	9.6E−7
CC	Mitochondrial matrix	38	3.7	3.1E−7	4.5E−4
CC	Cytosol	200	19.7	9.1E−6	1.3E−2
CC	Mitochondrial intermembrane space	14	1.4	2.5E−5	3.7E−2

The number of genes, along with the corresponding P-value and FDR are also reported. The fold-change of the differentially expressed genes has been set at 2.5.

AMA, advanced maternal age; BP, biological process; CC, cellular component; FDR, false discovery rate; MII oocyte; YMA, young maternal age.