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. Author manuscript; available in PMC: 2022 Jan 5.
Published in final edited form as: Neurobiol Aging. 2021 Jan 15;101:85–93. doi: 10.1016/j.neurobiolaging.2021.01.002

Table 1.

Demographic and clinical characteristics for late-life depressed (LLD) patients and controls

Demographic variable Healthy older controls (n = 21) LLD patients (n = 21) at baseline LLD patients (n = 20) during SSRI treatment
Age 66 ± 6 67 ± 7
Sex (F/M) 11/10 11/10
Education (in years) 15 ± 3 15 ± 2
Race (number of participants who are African American/White) 1/20 2/19 2/18
MMSE 29 ± 1 29 ± 1 29 ± 1
HDRS 1 ± 1 17 ± 2a 5 ± 3b
BDI 6 ± 12 24 ± 8c 9 ± 7d
CVLT total recall (sum of first 5 trials) 59 ± 11 56 ± 10 58 ± 9
CVLT delayed free recall 12 ± 2 12 ± 3 13 ± 3
DKEFS™ Category fluency 41 ± 8 41 ± 8 42 ± 2
DKEFS™ Letter fluency 45 ± 12 40 ± 11 45 ± 12e
BVMT-R total recall (sum of first 3 trials) 19 ± 7 20 ± 8 24 ± 6f
BVMT-R delayed recall 8 ± 3 7 ± 3 9 ± 3g,h
Rey complex figure test-copy 32 ± 3 31 ± 4 32 ± 3
Rey complex figure test-immediate recall 17 ± 6 16 ± 7 22 ± 7i
Rey complex figure test-delayed recall 16 ± 5 15 ± 6 22 ± 7j

Key: BDI, Beck Depression Inventory; BVMT-R, Brief Visual Memory Test-Revised; CVLT, California Verbal Learning Test; D-KEFS, Delis-Kaplan Executive Function System; HDRS, Hamilton Depression Rating Scale; MMSE, modified Mini-Mental State Examination; SSRI, Selective Serotonin Reuptake Inhibitor.

a

Significant difference between controls and LLD patients (F(1,40) = 900.42, p < 0.001).

b

Significant difference in the LLD patients before and during SSRI treatment (F(1,19) = 229.31, p < 0.001).

c

Significant difference between controls and LLD patients (F(1,40) = 35.51, p < 0.001).

d

Significant difference in the LLD patients before and during SSRI treatment (F(1,19) = 42.52, p < 0.001).

e

Significant difference in the LLD patients before and during SSRI treatment (F(1,19) = 4.96, p < 0.05).

f

Significant difference in the LLD patients before and during SSRI treatment (F(1,19) = 8.77, p < 0.01).

g

Significant difference in the LLD patients before and during SSRI treatment (F(1,19) = 16.00, p < 0.001).

h

Significant change in performance between controls and LLD patient groups (F(1,19) = 8.59, p < 0.01).

i

Significant difference in the LLD patients before and during SSRI treatment (F(1,19) = 38.30, p < 0.001).

j

Significant difference in the LLD patients before and during SSRI treatment (F(1,19) = 65.07, p < 0.001).