Table 3.
Positive correlations between greater beta-amyloid (Aβ) deposition and greater depressive symptoms (Hamilton Depression Rating Scale) in late-life depressed (LLD) patients and healthy controls
| Left hemisphere |
Structure | ||
|---|---|---|---|
| MNI coordinates |
Talairach coordinates |
Z-score | |
| X Y Z (mm) | X Y Z (mm) | ||
| −50 −52 54 | −50 −49 50 | 3.07 | Supramarginal gyrus (BA 39) |
| −24 −74 56 | −24 −69 51 | 3.50 | Superior parietal lobule (BA 7) |
| −26 −72 42 | −26 −68 39 | 3.41 | Inferior parietal lobule (BA 7) |
| −38 −76 46 | −38 −72 43 | 3.30 | Inferior parietal lobule (BA 39) |
The results are reported at a significance level of cluster-level, family-wise error (FWE) corrected threshold of p ≤ 0.05 and a peak voxel uncorrected threshold of p ≤ 0.001: Height threshold p = 0.01 and extent threshold (k) = 50 voxels. The cluster size (kE) is 2276. Note: No effects in the right hemisphere were observed.
Key: BA, Brodmann area; MNI, Montreal Neurological Institute (MNI).