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. 2022 Jan 5;121:46–55. doi: 10.1016/j.humpath.2021.12.012

Table 1.

Pregnancy outcome and maternal and placental characteristics.

Cases Age of onset of maternal symptoms (WoG) Term of delivery (WoG) Time between maternal symptoms and delivery (days) Pregnancy outcome Maternal symptoms Fetal weight (g) Fetal weight (percentile) Histological placental lesions
1 32 34 + 1 15 IUFD Influenza-like illness + hyperthermia 1640 3-5th Diffuse TN + intervillositis + PFD + IH
2 21 23 14 IUFD Influenza-like illness 585 <3rd Diffuse TN + intervillositis + PFD + IH
3 18 + 4 19 + 4 7 IUFD Influenza-like illness 240 <3rd Diffuse TN + intervillositis + PFD + IH
4 19 + 3 21 11 IUFD Hyperthermie 380 10-25th Diffuse TN + intervillositis + PFD + IH
5 34 36 + 6 20 IUFD Influenza-like illness 2990 50th Diffuse TN + intervillositis + PFD + IH
6 unknown 38 + 5 unknown Cesarean section for bradycardia and preeclampsia live newborn Hyperthermia 2440 <5th Focal TN + intervillositis + PFD
7 30 33 21 Cesarean section live newborn Influenza-like illness 1940 20-50th Focal TN + intervillositis + PFD
8 33 33 0 Cesarean section live newborn Influenza-like illness 1730 30th Focal TN + intervillositis + PFD
9 35 37 + 3 18 Cesarean section live newborn Asymptomatic 2465 10-25th Focal TN + intervillositis + PFD
10 35 + 4 40 + 4 35 Vaginal delivery live newborn Hyperthermia 2860 5-10th Focal TN + intervillositis + PFD
11 32 39 49 Vaginal delivery live newborn Influenza-like illness 2550 3-5th MVM
12 25 36 + 5 82 Vaginal delivery live newborn Hypoxemic pneumonia 4250 95th Normal
13 31 32 7 Cesarean section live newborn Hypoxemic pneumonia 1800 70th Normal
14 32 33 7 Cesarean section live newborn Influenza-like illness 1700 30th Normal
15 31 + 3 37 45 Cesarean section live newborn Asymptomatic 3100 >75th Normal
16 30 30 + 5 5 Cesarean section live newborn Hypoxemic pneumonia 1600 >50th MVM
17 39 41 14 Vaginal delivery live newborn Asymptomatic 4210 >95th MVM
18 35 39 + 4 32 Vaginal delivery live newborn Asymptomatic 3350 >95th Normal
19 38 + 2 39 + 2 7 Cesarean section live newborn Unknown 2890 25th Normal
20 29 + 2 30 5 Cesarean section live newborn Hypoxemic pneumonia 1620 >75th Chorangiosis
21 28 28 + 2 2 Cesarean section live newborn Hypoxemic pneumonia 1100 >50th Chorangiosis
22 37 39 + 1 15 Vaginal delivery live newborn Unknown 2250 <3rd MVM
23 35 38 + 1 22 Vaginal delivery live newborn Hypoxemic pneumonia 3350 >75th Normal
24 33 + 2 34 + 1 6 Cesarean section live newborn Hypoxemic pneumonia 1935 >25th MVM
25 13 40 + 6 195 Vaginal delivery live newborn Influenza-like illness 2680 <3rd MVM
26 34 + 2 41 + 5 46 Vaginal delivery live newborn Hypoxemic pneumonia 3300 25th Normal
27 28 33 + 3 38 Vaginal delivery live newborn Unknown 2130 >75th MVM
28 25 40 + 4 109 Vaginal delivery live newborn Influenza-like illness 3730 59th Normal
29 34 + 3 39 + 4 36 Vaginal delivery live newborn Unknown 3120 >25th MVM
30 26 38 + 2 86 Vaginal delivery live newborn Unknown 2990 47th Normal
31 31 + 4 32 + 6 9 Vaginal delivery live newborn Hypoxemic pneumonia 1505 25th FVM
32 Unknown 29 Unknown Vaginal delivery live newborn Unknown 1230 >50th Chorioamnionitis
33 34 + 5 34 + 6 1 Cesarean section live newborn Asymptomatic 2350 >25th MVM
34 17 18 + 5 12 Twins pregnancy: miscarriage Unknown 120 and 240 10th and >50th Chorioamnionitis
35 36 39 21 Vaginal delivery live newborn Asymptomatic 3840 >95th Normal
36 21 38 119 Vaginal delivery live newborn Influenza-like illness 3715 >95th MVM
37 32 39 49 Vaginal delivery live newborn Influenza-like illness 3440 >50th Normal
38 33 + 1 41 55 Vaginal delivery live newborn Unknown 4200 90th MVM + chorioamnionitis
39 31 37 42 Vaginal delivery live newborn Unknown 3390 >75th Normal
40 4 41 259 Vaginal delivery live newborn Influenza-like illness Unknown x Normal
41 10 39 + 6 209 Vaginal delivery live newborn Unknown 3090 20th Focal intervillositis
42 28 39 77 Vaginal delivery live newborn Influenza-like illness 3470 47th Chorioamnionitis
43 4 39 245 Vaginal delivery live newborn Unknown 3600 75th Normal
44 34 + 3 39 + 4 36 Vaginal delivery live newborn Unknown 3120 25th MVM
45 18 + 5 28 + 5 70 Vaginal delivery live newborn Unknown 1030 and 1220 25th and 50th MVM
46 34 40 + 4 46 Vaginal delivery live newborn Unknown 3470 60th Chorioamnionitis
47 32 40 + 2 58 Vaginal delivery live newborn Unknown Unknwon X MVM + chorioamnionitis
48 13 23 + 3 73 Miscarriage 430 NA X MVM + chorioamnionitis
49 20 + 3 40 + 3 143 Vaginal delivery live newborn Unknown 3260 40th MVM + chorioamnionitis
50 24 39 + 5 110 Vaginal delivery live newborn Unknown 3260 25th MVM

Abbreviations: IUFD, intrauterine fetal death; TN, trophoblastic necrosis; PFD, perivillous fibrin deposition; IH, intervillous hemorrhage; MVM, maternal vascular malperfusion; FVM, fetal vascular malperfusion.