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. 2022 Jan 4;12(5):2206–2223. doi: 10.1016/j.apsb.2021.12.021

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© 2022 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

(A) Gold nanoparticle (GNP) decorated with high-mannoside-type oligosaccharides (P1@HM) and HIV-1-peptides-pulsed DC for HIV-specific T cell immunity. Reprinted with permission from Ref. 156 © Copyright 2018. Elsevier. (B) Fabrication of PLGA nanoparticle loaded with tumor antigen, metformin and hollow gold nanospheres (TA-Met@MS) as tumor vaccines. Photothermal therapy (PTT) stimulate the nanoparticle to release antigen and drug for inducing immunogenicity. (C) TA-Met@MS treatment prolonged the survival of tumor bearing mice and suppressed tumor progression. Reprinted with permission from Ref. 168. Copyright © 2021 Elsevier.