Fig 2. Homology model of MMAR_2193 with interacting S-adenosyl homocysteine (SAH) and S-adenosyl L-methionine (SAM).

Template structure of 4NEC_A from Protein Data Bank (PDB) was used to generate homology model using Biovia Discovery study version 4.5. The interaction between protein and methyl donor, SAM (B) and reduced SAH (A) was derived using CHARM based force field. Methyl group of SAM is shown in black color.