Table 1. Baseline, clinical and laboratories characteristics of study patients.
| Variable | Total (N = 326) | Severe dengue (N = 99) | Non severe dengue (N = 227) |
|---|---|---|---|
| n (%) | n (%) | n (%) | |
| Baseline characteristics | |||
| Gender | |||
| • Male | 166 (50,9) | 51 (51.5) | 115 (50.7) |
| • Female | 160 (49,1) | 48 (48.5) | 112 (49.3) |
| Age | |||
| • 6–10 years | 32 (9.8) | 10 (10.1) | 9.7) |
| • 11–20 years | 112 (34.4) | 26 (26.3) | 37.9) |
| • 21–30 years | 89 (27.3) | 37 (37.4) | 22.9) |
| • 31–40 years | 44 (13.5) | 8 (8.1) | 15.9) |
| • 41–50 years | 32 (9.8) | 12 (12.1) | 8.8) |
| • ≥ 51 years | 17 (5.2) | 6 (6.1) | 11 (4.8) |
| Underlying disease | |||
| • Yes | 40 (12.3) | 11 (11.1) | 12.8) |
| • No | 286 (87.7) | 88 (88.9) | 198 (87.2) |
| Clinical manifestations | |||
| Fever | 326 (100.0) | 99 (100.0) | 227 (100.0) |
| Skin rash | 251 (77.0) | 65 (65.7) | 186 (81.9) |
| Myalgia | 215 (66.0) | 60 (60.6) | 155 (68.3) |
| Haemorrhagic manifestations | 190 (58.3) | 56 (56.6) | 9.0) |
| • Petechiae | 106 (32.5) | 32 (32.3) | 32.6) |
| • Mucosal bleeding | 149 (45.7) | 41 (41.4) | 108 (47.6) |
| Vomiting and /or nausea | 159 (48.8) | 39 (39.4) | 120 (52.9) |
| Abdominal pain | 113 (34.7) | 36 (36.4) | 77 (33.9) |
| Loose stools | 54 (16.6) | 14 (14.1) | 40 (17.6) |
| Hepatomegaly | 13 (4.0) | 7 (7.1) | 6 (2.6) |
| Peripheral blood | |||
| • Hematocrit > 0.4 l/L | 208 (63.8) | 78 (78.8) | 9.9) |
| • WBC < 5 G/L | 257 (78.8) | 72 (72.7) | 1.5) |
| • Platelets ≤ 100 G/L | 213 (65.3) | 79 (79.8) | 134 (59.0) |
| Biochemical parameters | |||
| Creatinin > 120 μmol/L | 30 (9.2) | 30 (30.3) | 0 (0.0) |
| Liver enzymes | |||
| • AST > 40 U/L | 269 (82.5) | 87 (87.9) | 182 (80.2) |
| • ALT > 40 U/L | 210 (64.4) | 81 (81.8) | 129 (56.8) |
| Albumin < 35 g/L | 57 (17.5) | 32 (32.3) | 25/226 (11.1) |
| Bilirubin TT > 17 μmol/L | 39 (12.0) | 27 (27.3) | 12 (5.3) |
| Glucose | |||
| • ≤ 3.9 mmol/L | 6 (1.9) | 3/98 (3.1) | 3 (1.3) |
| • ≥ 6.4 mmol/L | 2 (0.6) | 0 (0.0) | 2/225 (0.9) |
| Coagulation parameters | |||
| • PT < 70% | 26 (8.0) | 13 (13.1) | 13 (5.7) |
| • PTs > 13 (s) | 90 (27.6) | 40 (40.4) | 50 (22.0) |
| • Fibrinogen < 2 g/L | 90 (27.9) | 42 (42.4) | 48 (21.1) |
| • aPTT > 40 (s) | 163 (50.0) | 49 (49.5) | 114 (50.2) |
| • INR > 1.25 (s) | 28 (8.6) | 11 (11.1) | 17 (7.5) |
| DENV type | |||
| • DEN-1 | 316 (96.9) | 94 (94.9) | 222 (97.8) |
| • DEN-2 | 10 (3.1) | 5 (5.1) | 5 (2.2) |