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. 2022 Jan 5;17(1):e0259753. doi: 10.1371/journal.pone.0259753

Table 1. Peak velocity of wild type and homozygous vmat2 mutant (HOM) larvae untreated (naïve) treated with pramipexole or L-Dopa.

Genotype Drug Dose Peak velocity (mm/s)  
  Mean ± SEM N
HOM Naïve   2.29 ± 0.11 53
Pramipexole 1μM 2.47 ± 0.190 18
10μM 2.37 ± 0.240 23
100μM 1.80 ± 0.170 24
L-Dopa 1μM 1.80 ± 0.160 13
10μM 2.03 ± 0.230 11
    100μM 2.20 ± 0.120 38
WT Naïve   1.22 ± 0.070 40
Pramipexole 1μM 1.23 ± 0.090 37
10μM 1.07 ± 0.100 24
100μM 1.11 ± 0.100 30
L-Dopa 1μM 1.22 ± 0.120 19
10μM 1.53 ± 0.150 14
    100μM 1.13 ± 0.080 28