Table 1:
Ancestry Group | Sample Size | Number of Cohorts | Mean Sample Size per Cohort (range) | Number of Variants |
---|---|---|---|---|
European | 1,320,016 | 146 | 10,928 (173-389,344) | 47 M |
East Asian | 146,492 | 40 | 7,448 (150-131,050) | 17 M |
Admixed African/African | 99,432 | 19 | 5,330 (473-62,022) | 33 M |
Hispanic | 48,057 | 10 | 6,032 (1,496-22,302) | 27 M |
South Asian | 40,963 | 7 | 6,413 (1,796-16,110) | 17 M |
Total | 1,654,960 | 201 | 52 M |
The present meta-analysis represents a 6-fold overall increase in sample size relative to the most recent 2018 Million Veteran Program blood lipid meta-analysis13, with a 2-fold increase in sample size of Admixed African and Hispanic individuals.