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. 2022 Jan 5;11:e73901. doi: 10.7554/eLife.73901

Figure 4. The precoupled complex of A2AR-Gsαβγ is stabilized by cholesterol.

Figure 4.

19F NMR spectra of apo A2AR in the presence of 0, 4, and 13% cholesterol, and as a function of Gαβγ. The key functional states are indicated by gray dashed lines and the three spectra in the presence of G protein are normalized via the A2 state.