Table 2.
Comparison of Baseline Characteristics Between Matched SRS and Conservative Management Cohorts
| SRS (n = 311) | Conservative Management (n = 311) | P Value | |
|---|---|---|---|
| Age, mean yr (SD) | 61.1 (12.9) | 60.7 (11.7) | 0.723a |
| Male, n (%) | 72/311 (23.2) | 63/311 (20.3) | 0.381 |
| Baseline KPS, median (IQR) | 90 (90-100) | 100 (90-100) | <0.001 |
| Diameter, mean mm (SD) | 19.0 (9.3) | 19.1 (8.9) | 0.876 |
| Volume, mean cm3 (SD) | 3.8 (3.3) | 3.9 (6.5) | 0.804a |
| Laterality, n (%) | 0.451 | ||
| Right | 140/307 (45.6) | 151/311 (48.6) | |
| Left | 149/307 (48.5) | 148/311 (47.6) | |
| Midline | 18/307 (5.9) | 12/311 (3.9) | |
| Location, n (%) | 0.798a | ||
| Skull base | 93/311 (29.9) | 95/311 (30.6) | |
| Convexity | 206/311 (66.2) | 207/311 (66.6) | |
| Other | 12/311 (3.9) | 9/311 (2.9) | |
| Margin dose, mean Gy (SD) | 12.9 (1.8) | –– | –– |
| Maximum dose, mean Gy (SD) | 26.0 (4.7) | –– | –– |
| Isocenters, median (IQR) | 9 (6–15) | –– | –– |
| Treatment volume, mean cm3 (SD) | 4.9 (4.1) | –– | –– |
| Imaging follow-up, mean mo (median; SD) | 46.5 (36; 35.5) | 46.6 (42; 28.3) | 0.961a |
| Clinical follow-up, mean mo (median; SD) | 47.4 (36; 36.1) | 46.6 (42; 28.3) | 0.767 |
Abbreviations: IQR, interquartile range; SD, standard deviation; SRS, stereotactic radiosurgery.
aMatched covariates.
Bold values are those with P < 0.05.