Table 6.
Lipinski’s rule of 5
| Phytochemicals | Mass | Hydrogen bond donor | Hydrogen bond acceptor | LOGP | Molar refractivity |
|---|---|---|---|---|---|
| Andrographolide | 350 | 3 | 5 | 1.96 | 93.5 |
| Bassic acid | 486 | 4 | 5 | 4.305 | 135.46 |
| Curdione | 236 | 0 | 2 | 3.55 | 69.73 |
| Nectandrin B | 344 | 2 | 5 | 4.19 | 94.21 |
| Nimbolide | 466 | 0 | 7 | 3.74 | 119.39 |
| Oleanolic acid | 456 | 2 | 3 | 7.233 | 132.68 |
| Panaxadiol | 460 | 2 | 3 | 6.74 | 133.81 |
| Panaxatriol | 476 | 3 | 4 | 5.71 | 135.20 |
| Salvicine | 330 | 2 | 4 | 2.86 | 93.96 |
| Tetrandine | 622 | 0 | 8 | 7.16 | 177.68 |
| Ursolic acid | 456 | 2 | 3 | 7.09 | 132.61 |
| Withaferin A | 470 | 2 | 6 | 3.35 | 124.46 |
| Hecogenin | 430 | 1 | 4 | 4.92 | 118.11 |
| Dovitinib (Standard drug) | 392 | 4 | 6 | 2.23 | 111.83 |
| Gefitinib (Standard drug) | 446.5 | 1 | 7 | 4.28 | 118.15 |