Table 2.
Examples of fluorescence imaging dye-encapsulated lipid nanoparticles
| Photoresponsive material | Nanocomposition | Wavelength (nm) | Application | Endpoint | References |
|---|---|---|---|---|---|
| ICG | DPPC | 808 | On-demand drug release | Proof-of-concept | Viitala et al. (2016) |
|
Lauric acid:Stearic acid = 4:1 (w/w) Gd − DTPA − SA:DSPE-mPEG2000-folic acid:Lecithin = 1:1:3 (w/w) |
808 |
PTT/PDT/ On-demand drug release |
In vivo study | Dai et al. (2019) | |
| IR780 |
DSPC:CfAc = 10:0.75 (w/w) DSPC:IR780 = 10:0.25 (w/w) |
808 | PDT | In vivo study | Appidi et al. (2020) |
| Methylene blue |
DPPC:Cholesterol:DOTAC = 1:0.5: (w/w) |
633 | PDT | In vitro study | Boccalini et al. (2017) |
ICG indocyanine green, DPPC 1,2-Dipalmitoyl-sn-glycero-3-phospho-choline, Gd-DTPA-SA gadolinium-diethylenetriaminepentaacetic dihydride-stearylamine, DSPC 1,2-distearoyl-sn-glycero-3-phosphocholine, DOTAC dimethyldioctadecylammonium chloride, PDT photodynamic therapy, PTT photothermal therapy