Table 6.
FDA-approved photodynamic therapy agents
| PDT agent | Photosensitizer | Approval year | Wavelength (nm) | Indication |
|---|---|---|---|---|
| Levulan® | PpIX | 1999 |
400–450 (Blu-U®) 600–650 (Aktilite™) |
Actinic keratoses on the face and scalp Squamous precancer of the skin |
| Photofrin® | Porfimer sodium | 2003 | 630 | Esophageal cancer |
| Metvix® | PpIX | 2004 |
630 570–670 |
Actinic keratoses on the face and scalp Basal cell carcinoma Unsuitable for other available therapies |
PpIX protoporphyrin IX, FDA Food and Drug Administration, PDT photodynamic therapy