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. 2022 Jan 6;96(2):431–451. doi: 10.1007/s00204-021-03202-0

Fig. 2.

Fig. 2

Mechanisms responsible for the molecular background of structural and functional changes in eye tissues in the course of methanol intoxication. Abbreviations: 5-HT serotonin, 5-HT2A serotonin 2A receptor, 5-HT2C serotonin 2C receptor, Asp aspartame, ATP adenosine triphosphate, GSH glutathione, IL-1β interleukin 1β, NF-ĸβ nuclear factor-kappa B, MDA malondialdehyde, Me-ION methanol-induced optic neuropathy, MPO myeloperoxidase, OSI oxidative stress index, ROS reactive oxygen species, SOD superoxide dismutase, TAS total anti-oxidant status, TNF-α tumor necrosis factor-alpha, TOS total oxidant status.