TABLE 2.
Redistribution of lysosomes by AR after BR treatment
Genotype | Subcellular localization of lysosomes (avg deviation)a
|
|
---|---|---|
% Clustered | Redistributed | |
+/+ | 3.0 (3.0) | 97.0 (3.0) |
Δ/Δ | 2.3 (1.1) | 97.7 (1.1) |
Cells were treated with BR for 30 min to induce perinuclear clustering of lysosomes. At 30 min after transfer to AR, the percentages of the cells with lysosomes redistributed to the cell periphery or remaining clustered around the nucleus were determined as described in Table 1.