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. 2021 Oct 23;41(2):147–158. doi: 10.1038/s41388-021-02069-w

Table 1.

Expression data for Gα12 and Gα13 in tumor tissues and cell lines, obtained either from (i) published reports, or (ii) database analysis (GEPIA, http://gepia.cancerpku.cn/index.html), as indicated.

Solid tumor types Gα12-mRNA tumor vs normal Gα12-protein tumor vs normal Gα13-mRNA tumor vs normal Gα13-protein tumor vs normal
Breast invasive carcinoma

No change

Source: GEPIA

High in metastatic tumors Source: Kelly et al. [17]

High in metastatic tumor cells

Source: Rasheed et al. [26]

High in metastatic tumor cells Source: Rasheed et al. [26]
Cervical carcinoma

Low in tumors

Source: GEPIA

P < 0.05

No report

No Change

Source: GEPIA

No report
Cholangiocarcinoma

High in tumors

Source: GEPIA p<0.05

No report

High in tumors

Source: GEPIA p<0.05

No report
Esophageal carcinoma

High in tumors

Source: GEPIA p<0.05

No report

High in tumors

Source: GEPIA p<0.05

No report
Glioblastoma multiforme

High in tumors

Source: GEPIA p<0.05

No report

High in tumors

Source: GEPIA p<0.05

No report
Head and neck squamous cell carcinoma

High in tumors

Source: GEPIA p<0.05

High in tumors and metastases Source: Liu et al. [23]

No Change

Source: GEPIA

High in tumors and metastases

Source: Rasheed et al. [28]

Lower grade glioma

High in tumors

Source: GEPIA p<0.05

No report

High in tumors

Source: GEPIA p<0.05

No report
hepatocellular carcinoma

No Change

Source: GEPIA

High in tumors and metastases Source: Yang et al. [24]

No Change

Source: GEPIA

No report
Ovarian serous cystadenocarcinoma

Low in tumors

Source: GEPIA p < 0.05

High in tumor cells

Source: Ha et al. [49, 50]

No Change

Source: GEPIA

High in tumor cells

Source: Cai and Xu [71]

Pancreatic adenocarcinoma

High in tumors

Source: GEPIA p<0.05

No report

High in tumors

Source: GEPIA p<0.05

No report
Prostate adenocarcinoma

No Change

Source: GEPIA

High in metastatic tumors

Source: Kelly et al. [17]

mRNA does not correlate to protein

Source: Rasheed et al. [25]

High in metastatic tumor cells

Source: Rasheed et al. [25]

Skin cutaneous melanoma

High in tumors

Source: GEPIA p<0.05

No report

High in tumors

Source: GEPIA p<0.05

No report
Stomach adenocarcinoma

High in tumors

Source: GEPIA p<0.05

No report

High in tumors

Source: GEPIA p<0.05

High in tumors and metastases

Source: Zhang et al. [27]

Thymoma

High in tumors

Source: GEPIA p<0.05

No report

No Change

Source: GEPIA

No report
Uterine corpus endometrial carcinoma

Low in tumors

Source: GEPIA p < 0.05

No report

No Change

Source: GEPIA

No report

Values in italic reflect that the expression was higher in tumor cells/tissues compared to normal cells/tissues, while bold indicates reduced expression.