Skip to main content
. 2021 Aug 21;15(1):74–83. doi: 10.1038/s41385-021-00441-3

Fig. 7. Ptpn2-LysMCre mice are more susceptible to Nippostrongylus brasilensis infection.

Fig. 7

7-week-old Ptpn2-LysMCre and their WT littermates were infected with 500 Nippostrongylus brasiliensis L3 stage larvae. a Weight development post infection, b representative pictures of lung histology and c respective scoring, d numbers of infiltrating cell, neutrophils, eosinophils, and macrophages as well as IL-4Ra expression on macrophages in BAL fluid at day 7. e, f levels of the indicated cytokines in e BAL fluid and f small intestinal homogenate on day 7 post infection. g Egg and worm count in the small intestine and the feces on day 7. h Alciane blue-PAS staining and goblet cell counts of small intestinal sections from mice on day 7. N.b. = Nippostrongylous brasiliensis infected. Representative results from one out of two independent experiments with 4-6 mice per group, each. * = p < 0.05, ** = p < 0.01, *** = p < 0.001, Kruskal–Wallis with Dunn’s multiple comparisons test.