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. Author manuscript; available in PMC: 2022 Jun 23.
Published in final edited form as: Nat Microbiol. 2021 Dec 23;7(1):73–86. doi: 10.1038/s41564-021-01010-x

Extended Data Fig. 1. Emergencia timonensis enables anaerobic metabolism of L-carnitine to TMA, via the intermediate γBB, in co-culture with bacterial species containing the cai operon.

Extended Data Fig. 1

(a) Quantification of d9-γBB to TMA pathway metabolites from 22 hour anaerobic mono- or co-cultures of representative bacterial species encoding either the caiTABCDE operon (P. mirabilis), the cntAB operon (K. pneumoniae) or both operons (E. fergusonii) and the strict anaerobe E. timonensis.

(b) Quantification of L-carnitine to TMA pathway metabolites (including γBB intermediate) in the same anaerobic mono- and co-cultures detailed in (a).

All biological replicates (n=3) are shown. Bar height represents the mean, error bars are ± one standard deviation from the mean.