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. 2021 Jun 10;16(1):54–68. doi: 10.1002/1878-0261.13017

Table 1.

Patient demographic and primary invasive tumor characteristics among WCHS cases included in the DSP assay. PR, progesterone receptor. Four staging categories, I–IV, from the American Joint Committee on Cancer were examined, stage 0 patients were not included in this study. Low tumor grade denotes well‐differentiated tumors, intermediate denotes moderately differentiated, and high grade denotes poorly differentiated tumors. Tumor size (cm) was classified into three categories: < 1.0 cm, 1.0–2.0 cm, and > 2.0 cm. LN, lymph node status was defined as the presence (positive) or no (negative) cancer cells in axillary lymph nodes.

Variable Categories Overall Black White P‐value
Overall 159 (100%) 94 (59.1%) 65 (40.9%)
Age Mean/(SD) 52.6/(10.2) 53.0/(10.7) 52.1/(9.6) 0.597
BMI < 25 46 (29.3%) 19 (20.2%) 27 (42.9%) 0.009
25–29 40 (25.5%) 27 (28.7%) 13 (20.6%)
30+ 71 (45.2%) 48 (51.1%) 23 (36.5%)
Subtype Luminal A 97 (61.8%) 52 (56.5%) 45 (69.2%) 0.005
HER2‐positive 26 (16.6%) 12 (13%) 14 (21.5%)
Triple‐negative 34 (21.7%) 28 (30.4%) 6 (9.2%)
ER status POS 112 (70.4%) 59 (62.8%) 53 (81.5%) 0.018
NEG 47 (29.6%) 35 (37.2%) 12 (18.5%)
PR status POS 92 (57.9%) 46 (48.9%) 46 (70.8%) 0.010
NEG 67 (42.1%) 48 (51.1%) 19 (29.2%)
HER2 status POS 26 (16.6%) 12 (13%) 14 (21.5%) 0.233
NEG 131 (83.4%) 80 (87%) 51 (78.5%)
Stage I 65 (41.1%) 31 (33%) 34 (53.1%) 0.028
II 72 (45.6%) 47 (50%) 25 (39.1%)
III/IV 21 (13.3%) 16 (17%) 5 (7.8%)
Grade LOW 22 (14.1%) 9 (9.8%) 13 (20.3%) 0.001
MED 53 (34%) 24 (26.1%) 29 (45.3%)
HIGH 81 (51.9%) 59 (64.1%) 22 (34.4%)
Tumor size < 1.0 18 (11.5%) 8 (8.6%) 10 (15.6%) 0.056
1–1.9 60 (38.2%) 31 (33.3%) 29 (45.3%)
≥ 2.0 79 (50.3%) 54 (58.1%) 25 (39.1%)
LN status POS 63 (41.2%) 42 (46.7%) 21 (33.3%) 0.138
NEG 90 (58.8%) 48 (53.3%) 42 (66.7%)

P‐values in bold are statistically significant.