Table 1.
Patient demographic and primary invasive tumor characteristics among WCHS cases included in the DSP assay. PR, progesterone receptor. Four staging categories, I–IV, from the American Joint Committee on Cancer were examined, stage 0 patients were not included in this study. Low tumor grade denotes well‐differentiated tumors, intermediate denotes moderately differentiated, and high grade denotes poorly differentiated tumors. Tumor size (cm) was classified into three categories: < 1.0 cm, 1.0–2.0 cm, and > 2.0 cm. LN, lymph node status was defined as the presence (positive) or no (negative) cancer cells in axillary lymph nodes.
Variable | Categories | Overall | Black | White | P‐value |
---|---|---|---|---|---|
Overall | 159 (100%) | 94 (59.1%) | 65 (40.9%) | ||
Age | Mean/(SD) | 52.6/(10.2) | 53.0/(10.7) | 52.1/(9.6) | 0.597 |
BMI | < 25 | 46 (29.3%) | 19 (20.2%) | 27 (42.9%) | 0.009 |
25–29 | 40 (25.5%) | 27 (28.7%) | 13 (20.6%) | ||
30+ | 71 (45.2%) | 48 (51.1%) | 23 (36.5%) | ||
Subtype | Luminal A | 97 (61.8%) | 52 (56.5%) | 45 (69.2%) | 0.005 |
HER2‐positive | 26 (16.6%) | 12 (13%) | 14 (21.5%) | ||
Triple‐negative | 34 (21.7%) | 28 (30.4%) | 6 (9.2%) | ||
ER status | POS | 112 (70.4%) | 59 (62.8%) | 53 (81.5%) | 0.018 |
NEG | 47 (29.6%) | 35 (37.2%) | 12 (18.5%) | ||
PR status | POS | 92 (57.9%) | 46 (48.9%) | 46 (70.8%) | 0.010 |
NEG | 67 (42.1%) | 48 (51.1%) | 19 (29.2%) | ||
HER2 status | POS | 26 (16.6%) | 12 (13%) | 14 (21.5%) | 0.233 |
NEG | 131 (83.4%) | 80 (87%) | 51 (78.5%) | ||
Stage | I | 65 (41.1%) | 31 (33%) | 34 (53.1%) | 0.028 |
II | 72 (45.6%) | 47 (50%) | 25 (39.1%) | ||
III/IV | 21 (13.3%) | 16 (17%) | 5 (7.8%) | ||
Grade | LOW | 22 (14.1%) | 9 (9.8%) | 13 (20.3%) | 0.001 |
MED | 53 (34%) | 24 (26.1%) | 29 (45.3%) | ||
HIGH | 81 (51.9%) | 59 (64.1%) | 22 (34.4%) | ||
Tumor size | < 1.0 | 18 (11.5%) | 8 (8.6%) | 10 (15.6%) | 0.056 |
1–1.9 | 60 (38.2%) | 31 (33.3%) | 29 (45.3%) | ||
≥ 2.0 | 79 (50.3%) | 54 (58.1%) | 25 (39.1%) | ||
LN status | POS | 63 (41.2%) | 42 (46.7%) | 21 (33.3%) | 0.138 |
NEG | 90 (58.8%) | 48 (53.3%) | 42 (66.7%) |
P‐values in bold are statistically significant.