Fig. 2.

Predictive capability of breast cancer risk markers in Sister Study testing set. Predictive capability of the mBCRS, PRS, and questionnaire‐based breast cancer risk factors (RFs) using receiver operating characteristics analysis; predictive capability reported as AUC. Questionnaire‐based risk factors include the following: age at blood draw, menopause status, body mass index, physical activity, alcohol consumption, age at first birth (among parous), total number of births, age at menarche, menopause age (among postmenopausal), smoking pack‐years, previous number of breast biopsies, family history of breast cancer (number of affected sisters, youngest proband sister age at diagnosis), educational attainment, and durations of postmenopausal hormone use and breastfeeding.