Fig. 6.

MiR-299 inhibitor or BACH1 overexpression reversed the repressive effects of SNHG5 knockdown on BC cell proliferation and glycolysis. BC cells transfected with sh-SNHG5 + miR-299 inhibitor, sh-SNHG5 + pcDNA3.1-BACH1 or their negative control. A Glucose consumption analysis and B lactate production were analyzed by kits. C HK2, PFK1 and GAPDH mRNA levels, D protein levels were detected by qRT-PCR, western blotting. β-Actin was used as an internal control. *p < 0.05, **p < 0.01, ***p < 0.001