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. 2021 Dec 23;8:788663. doi: 10.3389/fmed.2021.788663

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Copyright © 2021 Yao, Zhang, Yao, Ren, Xia, Jiang and Ding.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Activation of PPARα by FA repressed GFAP and COX2 expression in the retinas of IR rats. (A,B) Representative photomicrographs of immunostained GFAP/COX2 (red) and nuclei (blue; counterstained by DAPI) in retinal sections at 24 h post-modeling. (C) Retinal expression of GFAP, COX2, and actin detected by western blotting. (D,E) Average expression of GFAP/COX2 semi-quantified by densitometry and normalized by actin levels in retinas. Data are the mean ± SEM; **p < 0.01. Scale bar = 50 μm.