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. 2021 Dec 23;8:780329. doi: 10.3389/fmolb.2021.780329

TABLE 2.

Basic parameters of enhanced bootstrap in internal validation.

Parameters 1-year 3-years 5-years
C harrell apparent 0.7178 0.7178 0.7178
C time apparent 0.7678 0.7476 0.7352
Brier apparent 0.1396 0.2047 0.1396
C harrell optimism 0.0005 −0.0001 0.0010
C time optimism 0.0030 0.0032 0.0046
Brier optimism 0.0019 −0.0034 −0.0042
Optimism adjusted overall C statistics 0.7173 0.7179 0.7168
Optimism adjusted C statistics at time 0.7648 0.7444 0.7306
Optimism adjusted brier score 0.1414 0.2081 0.1437