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. 2021 Dec 23;12:798453. doi: 10.3389/fpsyt.2021.798453

Table 2.

Total effects of CBT on all outcomes.

Variables Studies (n) Participants (N) Mean difference Effect size Publication bias
Mean difference (95% CI) Q-test I2 (%) Standardized mean difference (95% CI) Q-test I2 (%) Egger's t (95% CI)
Insomnia Severity Index 20 1,398 −5.19*** (−6.30, −4.07) 1952.01*** 97.57*** −2.56*** (−3.81, −1.30) 516.28*** 98.89*** 1.05 (−0.89, 2.69)
Pittsburgh Sleep Quality Index 5 462 −3.13*** (−3.71, −2.56) 2.93 0.00 −0.96*** (−1.25, −0.68) 7.43 47.62 0.20 (−3.99, 4.52)
Total sleep time 25 1,523 23.21*** (14.56, 31.87) 235.35*** 83.31*** 0.63*** (0.28, 0.98) 215.91*** 91.20*** −0.18 (−1.19, 1.00)
Sleep efficiency 24 1,698 8.53*** (6.41, 10.65) 919.31*** 96.67*** 1.61*** (0.92, 2.29) 474.64*** 97.26*** 1.51(−0.36, 2.27)
Sleep onset latency 21 1,477 −16.43*** (−21.04, −11.81) 447.91*** 93.75*** −1.31*** (−2.00, −0.63) 367.33*** 97.09*** −0.87 (−2.02, 0.84)
Wake after sleep onset 20 1,387 −25.74*** (−32.46, −19.02) 217.21*** 92.56*** −1.44*** (−2.14, −0.74) 360.23*** 97.01*** −0.42 (−1.76, 1.18)
Number of awakenings 7 543 −0.69*** (−0.91, −0.46) 18.60** 72.02** −1.18* (−2.10, −0.26) 142.09*** 95.23*** 0.98 (−1.22, 2.71)
Depression 15 753 −3.67*** (−5.66, −1.68) 294.27*** 97.58*** −1.14** (−1.85, −0.42) 135.21*** 95.20*** 0.04 (−1.82, 1.89)
Anxiety 8 493 −0.66 (−1.53, 0.22) 73.20*** 88.09*** −0.62 (−1.55, 0.32) 67.90*** 95.83*** −0.86 (−1.89, 0.90)
Fatigue 6 426 −4.74* (−9.34, −0.14) 860.29*** 99.94*** −2.23** (−3.87, −0.58) 183.37*** 97.35*** −1.77 (−5.01, 1.43)
Physical health 3 369 1.90*** (1.02, 2.78) 1.01 0.00 0.42* (0.08, 0.76) 3.85 51.86 1.00 (−9.78, 11.45)
Mental health 3 369 4.95* (1.01, 8.90) 10.40** 80.07** 1.09 (−0.59, 2.77) 86.20*** 97.34*** −3.18 (−14.87, 8.91)

CI, confidence interval.

#x0002A;: p < 0.05,

**

p < 0.01,

***

p < 0.001.