GKCR method upregulated the P53/RB proteins and inhibited the proliferation and motility of the HeLa cells by targeting the HPV18 E6/E7 oncogenes
(A) Western blot analysis. ∗p < 0.05, ∗∗p < 0.01; analyzed by two-tailed Students’ t test. (B) CCK-8 assay. ∗p < 0.05, analyzed by two-way RM ANOVA with Sidak’s multiple comparisons test. (C) Wound healing assay; scale bars, 250 μm. ∗p < 0.05, ∗∗p < 0.01; analyzed by two-tailed Students’ t test.