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. 2021 Jul 18;13(1):188–200. doi: 10.1007/s13340-021-00522-5

Table 5.

Area under the curve, optimal cut-off points (using Youden Index) for MetS risk factors, and novel anthropometric indices in ROC analysis to identify MetS stratified by gender

Male Female
Variable AUC 95% CI Cut-off p* AUC 95% CI Cut-off p*
MetS risk factors
BMI 0.586 0.484–0.683  > 25.6 0.132 0.602 0.500–0.698  > 26.1 0.070
WC 0.628 0.526–0.722  > 100 0.021 0.700 0.601–0.787  > 92 0.001
WHR 0.753 0.658–.834  > 0.96 0.001 0.656 0.555–0.748  > 0.93 0.005
WHtR 0.804 0.714–0.877  > 0.58 0.001 0.837 0.751–0.903  > 0.59 0.001
FPG 0.921 0.850–0.965  > 105 0.001 0.961 0.903–0.989  > 94 0.001
HOMA-IR 0.635 0.534–0.729  > 1.25 0.015 0.765 0.670–0.844  > 3.65 0.001
TG/HDL 0.751 0.655 – 0.832  > 3.2 0.001 0.718 0.620–0.803  > 3.40 0.001
AIP 0.723 0.625–0.807  > 0.5 0.001 0.701 0.602–0.788  > 0.5 0.001
MAP 0.647 0.546–0.740  > 87.7 0.008 0.629 0.527–0.723  > 87.5 0.024
Fat percent 0.711 0.613–0.797  > 22.5 0.001 0.707 0.608–0.793  > 38.4 0.001
Novel anthropometric measures
ABSI 0.622 0.520–0.717  > 0.08 0.015 0.637 0.535–0.730  > 0.08 0.006
AVI 0.721 0.623–0.806  > 16.3 0.001 0.813 0.723–0.884  > 17 0.001
BAI 0.635 0.533–0.728  > 27.97 0.017 0.803 0.712–0.875  > 34.83 0.001
BRI 0.801 0.710–0.873  > 4.13 0.001 0.850 0.765–0.913  > 5.21 0.001
CI 0.770 0.676–0.848  > 1.09 0.001 0.797 0.705–0.871  > 1.03 0.001
LAP 0.655 0.554–0.747  > 66.93 0.004 0.681 0.581–0.770  > 53.65 0.001
VAI 0.760 0.665–0.840  > 4.6 0.001 0.693 0.605–0.787  > 4.5 0.002
WTI 0.701 0.599–0.788  > 116.65 0.001 0.768 0.673–0.846  > 141.08 0.001

Cut-off values corresponding with the highest Youden index

AUC area under the curve, 95% CI confidence interval, ROC receiver operating characteristic; and others as in Tables 1, 2, and 3

*Significant ability of each index to separate MetS and non MetS among male and female subjects