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. 2021 Dec 23;12:735071. doi: 10.3389/fneur.2021.735071

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Copyright © 2021 Korzowski, Weckesser, Franke, Breitling, Goerke, Schlemmer, Ladd, Bachert and Paech.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative ROI analysis of selected metabolite intensities from the patient with high-grade glioma (glioblastoma) shown in Figures 3, 4, given as mean (circles) ± standard deviation (bars). Only the α-ATP intensities are given in arbitrary units, and subject to the coil sensitivity profile; all other metabolites are quantified as ratios with respect to the α-ATP intensity. Number of voxels n in each ROI: n_WM = 8, n_GM = 8, n_GDCE = 173, n_NEC = 69.