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. 2021 Dec 23;12:735071. doi: 10.3389/fneur.2021.735071

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Copyright © 2021 Korzowski, Weckesser, Franke, Breitling, Goerke, Schlemmer, Ladd, Bachert and Paech.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bar plots illustrating the effects of the extended modeling on the quantification results within different ROIs (healthy and tumor tissues) from the patient with low-grade glioma (astrocytoma WHO 2) shown in Figure 2 (A–C) and the patient with high-grade glioma (glioblastoma) shown in Figures 3 and 4 (D–F). (A,D) Effect of DPG inclusion on the quantified intensities of PC and PE. (B,E) Effect of DPG inclusion on the ratios derived from PC and PE. (C,F) Effect of UDPG inclusion on the quantified intensities of NAD(H). The metabolites are quantified as ratios with respect to the α-ATP intensity.