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. 2021 Dec 23;12:735071. doi: 10.3389/fneur.2021.735071

Table 2.

ROI sizes for the individual subjects of the study cohort.

Subject WM left WM right GM left GM right WTV NEC GDCE ED
V1 15 12 14 14
V2 11 10 12 13
V3 6 7 10 9
LGG1 10 9 109
LGG2 7 8 201
HGG1 10 12 316 3 70 244
HGG2 9 14 422 38 126 266
HGG3 8 12 252 48 153 53
HGG4 9 12 339 48 90 204
HGG5 8 8 246 69 173 13

Given are the number of voxels within a region-of-interest (ROI) after mapping onto the phosphorus magnetic resonance spectroscopic imaging (31P MRSI) grid. White matter (WM) and gray matter (GM) ROIs were defined on both hemispheres for the volunteers (V1–V3), but only on the contralateral hemisphere for the patients (LGG1–HGG5). For the patients with low-grade glioma (LGG1 and LGG2), only the whole tumor volume (WTV) ROI was segmented. Note that in the case of patients with high-grade glioma (HGG1–HGG5), the number of voxels within the mapped WTV ROIs (defined as union of the individual segments on morphology) is not necessarily the sum of voxels in the separately mapped necrosis (NEC), gadolinium contrast enhancement (GDCE) and edema (ED) ROIs, because of voxel assignments to multiple ROIs by the mapping algorithm in some cases.