Table 2. Variables associated with S1-specific IgG and neutralizing Ab of ChAdOx1 nCoV-19 vaccine in multivariate analysis.
Variables | ChAdOx1 nCoV-19 1st dose (n=96) | ChAdOx1 nCoV-19 2nd dose (n=88) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Standardized β | p-value | Standardized β | p-value | R2 | Standardized β | p-value | Standardized β | p-value | R2 | |||
Log S1-specific IgG | ||||||||||||
Age | 0.006 | 0.96 | −0.03 | 0.77 | 0.05 | 0.69 | −0.01 | 0.94 | ||||
Female Sex | −0.10 | 0.40 | −0.13 | 0.29 | −0.02 | 0.91 | 0.01 | 0.92 | ||||
Occupation | ||||||||||||
Office worker | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref | ||||
Doctor | 0.08 | 0.56 | 0.09 | 0.52 | 0.11 | 0.45 | 0.11 | 0.44 | ||||
Nurse | 0.29 | 0.02 | 0.35 | 0.007 | 0.09 | 0.50 | 0.09 | 0.50 | ||||
Paramedic | 0.20 | 0.05 | 0.21 | 0.05 | 0.20 | 0.09 | 0.20 | 0.10 | ||||
Local reaction after each dose (sum of symptom score) | 0.30 | 0.003 | - | - | 0.19 | 0.29 | 0.01 | - | - | 0.11 | ||
Systemic reaction after each dose (sum of symptom score) | - | - | 0.08 | 0.47 | 0.11 | - | - | 0.14 | 0.20 | 0.05 | ||
Log 50% neutralizing Ab | ||||||||||||
Age | −0.02 | 0.84 | −0.07 | 0.53 | 0.12 | 0.33 | 0.09 | 0.48 | ||||
Female Sex | −0.06 | 0.64 | −0.07 | 0.58 | 0.07 | 0.60 | 0.11 | 0.44 | ||||
Occupation | ||||||||||||
Office worker | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref | ||||
Doctor | 0.21 | 0.12 | 0.22 | 0.11 | 0.07 | 0.64 | 0.07 | 0.63 | ||||
Nurse | 0.17 | 0.18 | 0.22 | 0.09 | 0.05 | 0.71 | 0.05 | 0.73 | ||||
Paramedic | 0.18 | 0.11 | 0.18 | 0.11 | −0.05 | 0.66 | −0.07 | 0.56 | ||||
Local reaction after each dose (sum of symptom score) | 0.22 | 0.04 | - | - | 0.10 | 0.19 | 0.10 | - | - | 0.05 | ||
Systemic reaction after each dose (sum of symptom score) | - | - | −0.03 | 0.81 | 0.06 | - | - | −0.003 | 0.98 | 0.02 |
Ref, reference value.