Table 3. Variables associated with S1-specific IgG and neutralizing Ab of BNT162b2 mRNA vaccine in multivariate analysis.
Variables | BNT162b2 mRNA 1st dose (n=35) | BNT162b2 mRNA 2nd dose (n=35) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Standardized β | p-value | Standardized β | p-value | R2 | Standardized β | p-value | Standardized β | p-value | R2 | |||
Log S1-specific IgG | ||||||||||||
Age | −0.08 | 0.69 | −0.07 | 0.74 | 0.12 | 0.56 | 0.16 | 0.42 | ||||
Female sex | 0.08 | 0.68 | 0.08 | 0.71 | 0.07 | 0.75 | 0.04 | 0.86 | ||||
Occupation | ||||||||||||
Doctor | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref | ||||
Nurse | −0.08 | 0.71 | −0.09 | 0.66 | −0.10 | 0.62 | −0.08 | 0.68 | ||||
Local reaction after each dose (sum of symptom score) | −0.06 | 0.77 | - | - | 0.02 | 0.03 | 0.89 | - | - | 0.03 | ||
Systemic reaction after each dose (sum of symptom score) | - | - | 0.02 | 0.91 | 0.01 | - | - | 0.19 | 0.33 | 0.06 | ||
Log 50% neutralizing Ab | ||||||||||||
Age | −0.02 | 0.93 | 0.03 | 0.87 | −0.15 | 0.45 | −0.14 | 0.49 | ||||
Female sex | 0.04 | 0.86 | 0.009 | 0.96 | 0.16 | 0.45 | 0.16 | 0.45 | ||||
Occupation | ||||||||||||
Doctor | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref | ||||
Nurse | 0.05 | 0.82 | −0.01 | 0.96 | 0.05 | 0.81 | 0.05 | 0.80 | ||||
Local reaction after each dose (sum of symptom score) | −0.10 | 0.60 | - | - | 0.01 | 0.03 | 0.88 | - | - | 0.08 | ||
Systemic reaction after each dose (sum of symptom score) | - | - | 0.18 | 0.35 | 0.03 | - | - | 0.05 | 0.81 | 0.08 |
Ref, reference value.