TABLE 3.
Models | circRNAs | Expression | Tissue | Target gene | References |
DNP | circ HIPK3 | ↑ | DRG | miR-124 | Wang L. et al., 2018 |
SNI | circ AnKsla | ↑ | Spinal cord | VEGFB | Zhang S.B. et al., 2019 |
CCI | ciRS-7 | ↑ | L4-L5 Spinal cord | miR-135a-5p | Cai et al., 2020 |
CCI | circ-0005075 | ↑ | L4-L6 dorsal spinal cord | miR-151a-3p/NOTCH2 | Zhang Y. et al., 2021 |
CCI | circ ZNF609 | ↑ | L4-L6 dorsal spinal cord | miR-22-3p/ENO1 | Li et al., 2020 |
CCI | circ ZRANB1 | ↓ | L4-L6 dorsal spinal cord | Wnt5a/β-catenin, miR-24-3p/LPAR3 | Wei et al., 2020 |
NP, Neuropathic pain; circRNAs, circular RNAs; DRG, dorsal root ganglion; CCI, chronic constriction injury; DNP, diabetic neuropathic pain; L4, lumbar 4; L5, lumbar 5; L6, lumbar 6; VEGFB, vascular endothelial growth factor B; ENO1, enolase 1; LPAR3, lysophosphatidic acid receptor 3.