Table 2.
HRV and outcome at 90 days.
| Death | Stroke | MI | MACE | mRS ≥ 2 | |
|---|---|---|---|---|---|
| OR (95% CI), p | OR (95% CI), p | OR (95% CI), p | OR (95% CI), p | OR (95% CI), p | |
| Model 1 | |||||
| SDNN daytime | 0.846 (0.749–0.956), p = 0.008 | 0.995 (0.965–1.026), p = 0.745 | 0.732 (0.462–1.159), p = 0.183 | 0.977 (0.947–1.008), p = 0.146 | 0.982 (0.966–0.998), p = 0.029 |
| RMSSD daytime | 0.834 (0.705–0.986), p = 0.034 | 0.985 (0.949–1.022), p = 0.408 | 0.674 (0.344–1.320), p = 0.25 | 0.966 (0.926–1.007), p = 0.103 | 0.993 (0.978–1.008), p = 0.353 |
| SDNN nighttime | 0.899 (0.819–0.986), p = 0.024 | 0.991 (0.969–1.015), p = 0.463 | 0.787 (0.55–1.128), p = 0.192 | 0.982 (0.959–1.006), p = 0.140 | 1.002 (0.992–1.011), p = 0.760 |
| RMSSD nighttime | 0.928 (0.85–1.013), p = 0.096 | 0.992 (0.968–1.016), p = 0.503 | 0.871 (0.653–1.162), p = 0.348 | 0.984 (0.958–1.011), p = 0.237 | 1.000 (0.991–1.009), p = 0.984 |
| LF daytime | 0.972 (0.938–1.007), p = 0.111 | 0.995 (0.971–1.019), p = 0.676 | 0.936 (0.849–1.031), p = 0.179 | 0.985 (0.965–1.006), p = 0.154 | 0.993 (0.981–1.005), p = 0.253 |
| HF daytime | 1.020 (0.976–1.065), p = 0.378 | 1.005 (0.975–1.036), p = 0.753 | 1.111 (0.973–1.267), p = 0.119 | 1.017 (0.991–1.043), p = 0.212 | 1.000 (0.985–1.016), p = 0.965 |
| LF nighttime | 0.995 (0.959–1.032), p = 0.775 | 0.991 (0.968–1.014), p = 0.424 | 0.968 (0.887–1.058), p = 0.447 | 0.992 (0.971–1.013), p = 0.445 | 0.993 (0.981–1.005), p = 0.228 |
| HF nighttime | 0.978 (0.931–1.027), p = 0.373 | 1.008 (0.981–1.036), p = 0.584 | 1.046 (0.941–1.163), p = 0.407 | 1.004 (0.980–1.029), p = 0.735 | 1.000 (0.987–1.014), p = 0.953 |
| LF/HF daytime | 0.762 (0.505–1.148), p = 0.193 | 0.917 (0.786–1.069), p = 0.266 | 0.067 (0–14.405), p = 0.325 | 0.876 (0.745–1.030), p = 0.109 | 1.004 (0.956–1.054), p = 0.886 |
| LF/HF nighttime | 1.025 (0.936–1.123), p = 0.593 | 0.893 (0.739–1.079), p = 0.239 | 0.394 (0.028–5.622), p = 0.492 | 0.969 (0.876–1.071), p = 0.539 | 1.015 (0.977–1.053), p = 0.449 |
| Model 2 | |||||
| SDNN daytime | 0.868 (0.769–0.979), p = 0.022 | n.a. | n.a. | n.a. | 0.984 (0.967–1.0), p = 0.052 |
| RMSSD daytime | 1.014 (0.998–1.031), p = 0.093 | n.a. | n.a. | n.a. | n.a. |
| SDNN nighttime | 0.914 (0.833–1.004), p = 0.06 | n.a. | n.a. | n.a. | n.a. |
| Model 3 | |||||
| SDNN daytime | 0.851 (0.733–0.988), p = 0.034 | n.a. | n.a. | n.a. | n.a. |
Logistic regression analysis according to three different models. Model 1: unadjusted. Model 2: adjusted for age and sex. Model 3: adjusted for age, sex, NIHSS, diabetes, coronary artery disease, medication with beta-blockers, RAAS (renin-angiotensin-aldosterone system) inhibitors and antidepressants. HRV, heart rate variability; OR, odds ratio; mRS, modified Rankin scale; MI, myocardial infarction; MACE, major cardiovascular adverse event, combination of recurrent stroke, myocardial infarction and death; SDNN, standard deviation of beat-to-beat (NN) intervals; RMSSD, Root Mean Square of Successive Differences; LF, low frequency power component; HF, high frequency power component.
The bold values represent statistically significant results.