Table 4.
Differentially abundance taxa between VB and CS groups in adults.
| Taxa | Taxonomic Level | VB | CS | P-value |
|---|---|---|---|---|
| Actinobacteria | p | 4.29 [2.95; 5.87] | 4.06 [2.52; 6.64] | 0.847 |
| Bacteroidetes | p | 13.7 [7.31; 19.7] | 15.7 [9.64; 22.0] | 0.448 |
| Firmicutes | p | 77.4 [71.5; 81.8] | 77.3 [72.1; 82.9] | 0.934 |
| Proteobacteria | p | 0.30 [0.20; 0.61] | 0.33 [0.15; 0.66] | 0.815 |
| Verrucomicrobia | p | 0.62 [0.02;2.16] | 0.02 [0.00;0.33] | 0.027 |
| Actinomycetaceae | f | 0.01 [0.00; 0.01] | 0.01 [0.01; 0.02] | 0.098 |
| Bifidobacteriaceae | f | 2.73 [1.98; 3.70] | 2.71 [1.30; 3.96] | 0.945 |
| Coriobacteriaceae | f | 1.55 [0.87; 2.15] | 1.13 [0.83; 2.28] | 0.491 |
| Bacteroidaceae | f | 5.45 [3.91; 11.0] | 9.19 [5.74; 14.0] | 0.092 |
| Porphyromonadaceae | f | 1.05 [0.52; 2.07] | 0.92 [0.53; 1.46] | 0.424 |
| Prevotellaceae | f | 0.46 [0.01; 4.30] | 0.12 [0.01; 1.82] | 0.624 |
| Rikenellaceae | f | 0.96 [0.52; 1.55] | 1.04 [0.37; 1.86] | 0.836 |
| Enterococcaceae | f | 0.01 [0.00; 0.03] | 0.01 [0.00; 0.02] | 0.195 |
| Lactobacillaceae | f | 0.01 [0.00; 0.09] | 0.01 [0.01; 0.03] | 0.689 |
| Streptococcaceae | f | 0.34 [0.13; 0.66] | 0.37 [0.16; 0.73] | 0.526 |
| Clostridiaceae_1 | f | 0.57 [0.21; 1.12] | 0.44 [0.11; 1.09] | 0.629 |
| Eubacteriaceae | f | 0.01 [0.01; 0.02] | 0.02 [0.01; 0.03] | 0.572 |
| Lachnospiraceae | f | 32.1 [27.5; 42.0] | 33.3 [29.6; 39.0] | 0.424 |
| Peptostreptococcaceae | f | 1.19 [0.62; 2.39] | 1.54 [0.60; 2.06] | 0.879 |
| Ruminococcaceae | f | 28.6 [24.7; 32.2] | 29.5 [23.7; 34.8] | 0.679 |
| Erysipelotrichaceae | f | 1.07 [0.54; 2.52] | 1.67 [0.84; 2.23] | 0.356 |
| Acidaminococcaceae | f | 0.07 [0.01; 1.15] | 0.47 [0.01; 1.52] | 0.244 |
| Veillonellaceae | f | 3.74 [1.38; 5.49] | 1.54 [0.18; 5.44] | 0.19 |
| Sutterellaceae | f | 0.10 [0.02; 0.22] | 0.05 [0.01; 0.18] | 0.436 |
| Desulfovibrionaceae | f | 0.07 [0.03; 0.12] | 0.04 [0.02; 0.15] | 0.639 |
| Enterobacteriaceae | f | 0.01 [0.00; 0.06] | 0.02 [0.01; 0.09] | 0.25 |
| Pasteurellaceae | f | 0.01 [0.00; 0.03] | 0.02 [0.00; 0.07] | 0.33 |
| Verrucomicrobiaceae | f | 0.62 [0.02;2.16] | 0.02 [0.00;0.33] | 0.027 |
| Actinomyces | g | 0.01 [0.00; 0.02] | 0.01 [0.01; 0.02] | 0.136 |
| Akkermansia | g | 0.65 [0.02;2.18] | 0.02 [0.00;0.34] | 0.025 |
| Alistipes | g | 0.96 [0.54; 1.56] | 1.06 [0.40; 1.89] | 0.858 |
| Anaerostipes | g | 1.26 [0.58; 1.59] | 1.14 [0.59; 2.03] | 0.689 |
| Asaccharobacter | g | 0.10 [0.04; 0.17] | 0.05 [0.02; 0.13] | 0.209 |
| Bacteroides | g | 5.90 [4.00; 11.0] | 9.67 [6.02; 15.6] | 0.098 |
| Barnesiella | g | 0.23 [0.12; 0.69] | 0.23 [0.15; 0.48] | 0.684 |
| Bifidobacterium | g | 2.75 [1.99; 3.76] | 2.85 [1.31; 3.99] | 0.912 |
| Bilophila | g | 0.05 [0.01; 0.09] | 0.03 [0.01; 0.08] | 0.535 |
| Blautia | g | 5.58 [4.52; 9.30] | 6.10 [4.48; 8.48] | 0.793 |
| Butyricicoccus | g | 0.43 [0.31; 0.59] | 0.41 [0.28; 0.66] | 0.783 |
| Butyricimonas | g | 0.02 [0.00; 0.04] | 0.02 [0.00; 0.05] | 0.792 |
| Clostridium_IV | g | 0.50 [0.23; 1.42] | 0.40 [0.26; 0.89] | 0.6 |
| Clostridium_sensu_stricto | g | 0.58 [0.21; 1.13] | 0.45 [0.11; 1.09] | 0.62 |
| Clostridium_XI | g | 1.19 [0.63; 2.43] | 1.55 [0.61; 2.10] | 0.858 |
| Clostridium_XlVa | g | 1.06 [0.77; 1.94] | 1.26 [0.92; 1.67] | 0.408 |
| Clostridium_XlVb | g | 0.05 [0.02; 0.17] | 0.04 [0.01; 0.14] | 0.517 |
| Clostridium_XVIII | g | 0.53 [0.18; 0.92] | 0.74 [0.27; 1.24] | 0.16 |
| Collinsella | g | 0.90 [0.63; 1.83] | 0.84 [0.50; 1.62] | 0.416 |
| Coprococcus | g | 3.32 [1.20; 6.18] | 2.13 [1.07; 3.76] | 0.195 |
| Dialister | g | 1.98 [0.74; 4.11] | 0.64 [0.01; 3.40] | 0.067 |
| Dorea | g | 1.41 [0.81; 1.96] | 1.64 [0.94; 2.56] | 0.264 |
| Eerthella | g | 0.00 [0.00; 0.02] | 0.00 [0.00; 0.02] | 0.814 |
| Enterococcus | g | 0.01 [0.01; 0.03] | 0.01 [0.00; 0.02] | 0.209 |
| Escherichia.Shilla | g | 0.01 [0.00; 0.06] | 0.01 [0.00; 0.05] | 0.71 |
| Eubacterium | g | 0.01 [0.01; 0.02] | 0.01 [0.01; 0.03] | 0.699 |
| Faecalibacterium | g | 13.1 [9.81; 16.0] | 11.9 [7.84; 15.7] | 0.535 |
| Flavonifractor | g | 0.03 [0.02; 0.04] | 0.02 [0.02; 0.10] | 0.61 |
| Gemmir | g | 1.11 [0.57; 1.78] | 1.15 [0.64; 2.51] | 0.572 |
| Gordonibacter | g | 0.01 [0.00; 0.03] | 0.01 [0.00; 0.02] | 0.571 |
| Haemophilus | g | 0.01 [0.00; 0.04] | 0.02 [0.00; 0.06] | 0.374 |
| Holdemania | g | 0.01 [0.01; 0.01] | 0.01 [0.01; 0.02] | 0.581 |
| Lachnospira | g | 0.23 [0.02; 0.72] | 0.24 [0.03; 1.12] | 0.836 |
| Lactobacillus | g | 0.01 [0.00; 0.09] | 0.01 [0.01; 0.03] | 0.689 |
| Odoribacter | g | 0.07 [0.02; 0.17] | 0.06 [0.02; 0.16] | 0.783 |
| Oscillibacter | g | 0.20 [0.09; 0.29] | 0.17 [0.08; 0.39] | 0.858 |
| Parabacteroides | g | 0.59 [0.28; 0.84] | 0.41 [0.25; 0.83] | 0.491 |
| Parasutterella | g | 0.01 [0.00; 0.07] | 0.01 [0.00; 0.02] | 0.562 |
| Phascolarctobacterium | g | 0.01 [0.00; 0.55] | 0.22 [0.00; 1.36] | 0.214 |
| Prevotella | g | 0.07 [0.00; 4.29] | 0.01 [0.00; 1.71] | 0.276 |
| Roseburia | g | 7.48 [6.28; 13.2] | 10.4 [5.73; 12.3] | 0.639 |
| Ruminococcus | g | 4.59 [3.23; 6.60] | 5.35 [1.66; 7.42] | 0.526 |
| Ruminococcus2 | g | 1.16 [0.93; 1.81] | 1.23 [0.72; 1.87] | 0.783 |
| Streptococcus | g | 0.34 [0.12; 0.68] | 0.37 [0.14; 0.65] | 0.699 |
| Sutterella | g | 0.01 [0.00; 0.15] | 0.02 [0.00; 0.11] | 0.78 |
| Turicibacter | g | 0.04 [0.01; 0.14] | 0.08 [0.01; 0.20] | 0.416 |
| Veillonella | g | 0.04 [0.01; 0.12] | 0.06 [0.01; 0.19] | 0.62 |
Relative abundance data (Median [1st Quartile; 3rd Quartile] at phylum (p), family (f) and genus (g) level, as tested with a Mann-Whitney U test. The p-values are correct for multiple testing at a defined false discovery. Significant effects (p < 0.05) are given in bold. Vaginal birth = VB; C-section = CS.