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. 2021 Dec 23;12:791099. doi: 10.3389/fimmu.2021.791099

Figure 2.

Figure 2

Expression of pro-inflammatory miRNAs in TABs from GCA and non-GCA patients. (A) Expression of pro-inflammatory miRNAs in TAB-positive GCA arteries [TAB(+/+), n = 30], TAB-negative GCA arteries [TAB(-/+), n = 16] and non-GCA temporal arteries [TAB(-/-), n = 22]. The bars represent the means of log2 fold change values ± S.D. Data were evaluated using the Mann-Whitney U test. An asterisk indicates significance to the TAB(-/-) group (*p < 0.05; ***p < 0.001) and the letter a the significance between the TAB(+/+) and TAB(-/+) groups (a p < 0.01; aa p < 0.001). (B) Association (Spearman’s ρ correlation coefficients) between miRNA expression levels and evaluated histopathological parameters in TABs from GCA patients (n = 46). A p-value of < 0.05 was considered statistically significant in all cases.