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. 2021 Dec 23;12:791099. doi: 10.3389/fimmu.2021.791099

Table 3.

Spearman’s correlation matrix of associations between symptom duration, histopathological and laboratory parameters of GCA patients.

Histopathological parameter GCA symptom duration ESR CRP Platelets Hemoglobin Fibrinogen
[days] [mm/h] [mg/ml] [109/l] [mg/ml] [mg/ml]
CD3+ [cells/mm2] 0.144 –0.050 0.195 0.048 0.164 –0.011
CD4+ [cells/mm2] 0.186 –0.036 0.204 0.044 0.176 –0.007
CD8+ [cells/mm2] 0.068 0.040 0.239 0.113 0.088 0.130
CD4+:CD8+ ratio –0.046 0.076 –0.263 –0.003 0.025 –0.132
NFATC+ [cells/mm2] 0.161 0.027 0.213 0.085 0.184 0.041
NFATC+:CD4+ ratio –0.079 0.190 0.209 0.188 0.106 0.280
CD20+ [cells/mm2] 0.100 –0.143 0.084 0.032 0.191 0.078
CD68+ [score] 0.091 0.024 0.248 0.128 0.038 0.220
MGCs [score] 0.074 0.062 0.313* 0.134 0.090 0.113
Eosinophils [score] –0.110 0.108 0.344* 0.130 0.177 0.091

ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; MGC, multinucleated giant cell. Spearman’s correlation coefficients (ρ) between evaluated parameters of 46 GCA patients, including 30 TAB-positive and 16 TAB-negative GCA patients. A p-value of < 0.05 was considered statistically significant (*p < 0.05) (marked in bold).