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. 2021 Dec 23;12:742654. doi: 10.3389/fneur.2021.742654

Table 3.

Model performance validation for PD classification.

Validation dataset LR NB RF
AUC ACC AUC ACC AUC ACC
Finger tapping
Single hand Amplitude_mean 0.472 0.333 0.583 0.500 0.458 0.500
(unilateral)l Amplitude_std 0.583 0.500 0.472 0.500 0.458 0.417
Speed 1.000 1.000 0.833 0.667 0.750 0.667
Fatigue 0.722 0.583 0.611 0.583 0.417 0.500
Two-hands Amplitude_mean 0.777 0.750 0.750 0.500 0.556 0.417
(bilateral) Amplitude_std 0.444 0.500 0.500 0.583 0.597 0.583
Speed 0.208 0.500 0.125 0.250 0.458 0.417
Fatigue 0.500 0.416 0.222 0.500 0.556 0.500
Hand movements
Single hand Amplitude_mean 0.639 0.667 0.417 0.500 0.528 0.583
(unilateral) Amplitude_std 0.278 0.500 0.222 0.333 0.486 0.417
Speed 1.000 1.000 0.972 0.917 0.778 0.583
Fatigue 0.472 0.417 0.750 0.583 0.556 0.583
Two-hands Amplitude_mean 0.750 0.667 0.528 0.667 0.292 0.250
(bilateral) Amplitude_std 0.472 0.500 0.528 0.417 0.708 0.667
Speed 0.389 0.417 0.389 0.500 0.056 0.250
Fatigue 0.333 0.417 0.500 0.417 0.569 0.583
Pronation-supination movement of the hands
Single hand Amplitude_mean 0.917 0.667 0.778 0.750 0.667 0.417
(unilateral) Amplitude_std 0.944 0.917 0.889 0.917 0.889 0.833
Speed 0.750 0.750 0.417 0.250 0.611 0.667
Fatigue 0.444 0.417 0.611 0.500 0.778 0.750
Two-hands Amplitude_mean 0.833 0.750 0.861 0.833 0.542 0.500
(bilateral) Amplitude_std 0.611 0.750 0.861 0.750 0.625 0.583
Speed 0.611 0.583 0.750 0.750 0.750 0.750
Fatigue 0.306 0.333 0.583 0.583 0.306 0.500

Validation results of the combined right and left motor features for PD classification. The validation was made using three classifiers: Logistic regression (LR), Gaussian Naïve-Bayes (NB), and Random Forest (RF). Features with cross-validation AUC > 0.6 are highlighted in bold. Units: normalized amplitude [0–1] for finger tapping and hand movements; amplitude (degrees) for pronation supination for amplitude features. Time (frames), for speed in all the tasks. AUC, cross-validation area under curve; ACC, accuracy.