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. 2021 Nov 15;106(1):275–282. doi: 10.4269/ajtmh.21-0532

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© 2022 by The American Society of Tropical Medicine and Hygiene

This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Figure 2. — Reactivity of recombinant and native pLDH proteins. Any samples showing antigen-negative results by the 5-Plex were excluded from analysis. Depicted are box and whisker plots for ratios of PanLDH/PfLDH for the P. falciparum, P. malariae, and P. ovale columns or ratio of PanLDH/PvLDH for the P. vivax column for each source of pLDH (recombinant and native). The ends of the boxes correspond to the 25th and 75th percentiles, respectively, and the middle line corresponds to the median. Two-way ANOVA plus Sidak multiple comparison test was used to determine the statistical significance against ratio values of P. falciparum. Significant differences (**** P < 0.0001, ** P < 0.001).