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. 2021 Nov 1;106(1):54–59. doi: 10.4269/ajtmh.21-0548

Table 1.

Hematological and biochemical investigations and their association with clinical risk factors

N (%)
Variable Lymphopenia Neutrophilia Uremia Low bicarbonate Elevated INR
Age 18–49 25/34 (74) 26/34 (76) 8/34 (24) 17/37 (46) 18/23 (78)
50–69 42/59 (71) 33/59 (56) 26/59 (44) 22/60 (37) 24/37 (65)
70–99 26/29 (90) 21/29 (72) 16/29 (55) 8/31 (26) 10/17 (59)
P value 0.15 0.09 0.03 * 0.23 0.3
Sex Male 61/77 (79) 52/77 (65) 30/77 (39) 28/82 (34) 35/49 (71)
Female 32/45 (71) 28/48 (62) 20/45 (44) 19/46 (41) 17/28 (61)
P value 0.31 0.55 0.55 0.42 0.33
ATSI Yes 26/33 (79) 27/33 (81) 12/33 (36) 15/34 (44) 16/20 (80)
No 62/80 (78) 48/80 (60) 3/80 (46) 31/81 (38) 33/54 (61)
P value 0.88 0.02 * 0.33 0.56 0.13
Diabetes mellitus Yes 46/58 (79) 41/58 (71) 27/58 (47) 24/59 (41) 24/37 (65)
No 47/64 (73) 39/64 (61) 23/64 (36) 23/65 (35) 28/40 (70)
P value 0.45 0.25 0.23 0.54 0.63
Alcohol excess Yes 51/64 (80) 44/64 (69) 24/64 (38) 25/46 (54) 32/42 (76)
No 39/53 (74) 33/53 (62) 24/53 (45) 21/53 (40) 19/34 (56)
P value 0.43 0.46 0.39 0.85 0.06
Chronic kidney disease Yes 7/7 (100) 5/7 (71) 7/7 (100) 4/7 (57) 2/5 (40)
No 78/107 (73) 68/107 (64) 38/107 (36) 40/107 (37) 48/70 (69)
P value 0.12 1.00 0.001 * 0.29 0.33
Lung disease Yes 29/35 (83) 31/35 (89) 16/35 (46) 17/37 (46) 13/21 (62)
No 64/87 (74) 49/87 (56) 34/87 (39) 30/87 (34) 39/56 (70)
P value 0.27 0.001 * 0.50 0.23 0.52
Immunosuppression Yes 9/12 (75) 4/12 (33) 4/12 (33) 6/12 (50) 5/8 (63)
No 84/110 (76) 76/110 (69) 46/110 (42) 41/110 (37) 47/69 (68)
P value 0.92 0.02 * 0.57 0.39 0.75
Malignancy Yes 13/16 (81) 9/16 (56) 8/16 (50) 3/16 (19) 9/12 (75)
No 80/106 (75) 71/106 (67) 42/106 (40) 44/106 (42) 43/65 (66)
P value 0.76 0.40 0.43 0.08 0.74
No risk factor† Yes 6/13 (46) 3/13 (23) 4/13 (31) 3/13 (23) 6/10 (60)
No 86/107 (80) 75/107 (70) 45/107 (42) 42/112 (38) 44/65 (68)
P value 0.006 * 0.001 * 0.43 0.30 0.63

ATSI = Aboriginal and Torres Strait Islander; INR = international normalized ratio.

*

Denotes statistical significance.

Excludes age and sex.