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. 2021 Dec 23;12:786554. doi: 10.3389/fimmu.2021.786554

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Copyright © 2021 Xu, Xue, Xiao, Jia, Wu, Liu, Li, Liang and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anti-SARS-CoV-2 antibody response and duration after vaccination over time. The levels and half-lives of neutralizing antibody (A), anti-RBD total antibody (B), anti-Spike IgG (C), anti-Spike IgM (D), and anti-Spike IgA (E) were determined after vaccination over time. There were significant differences with repeated-measures ANOVA in all of antibodies (P < 0.05). The decay half-lives for individuals were estimated using a linear mixed effects model with censoring of titers below the positive threshold. Receive vaccine .

Inline graphic — Anti-SARS-CoV-2 antibody response and duration after vaccination over time. The levels and half-lives of neutralizing antibody (A), anti-RBD total antibody (B), anti-Spike IgG (C), anti-Spike IgM (D), and anti-Spike IgA (E) were determined after vaccination over time. There were significant differences with repeated-measures ANOVA in all of antibodies (P < 0.05). The decay half-lives for individuals were estimated using a linear mixed effects model with censoring of titers below the positive threshold. Receive vaccine .