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. 2021 Dec 23;9:811666. doi: 10.3389/fcell.2021.811666

FIGURE 4.

FIGURE 4

A possible mechanism of action of exosomal non-coding RNAs in osteoporosis (schematic). Different sources of exosomal non-coding RNAs, such as miRNA, lncRNA, circRNA, and tRNA, promote or inhibit the activity of osteoblasts and osteoclasts by regulating different targets, thereby affecting the course of osteoporosis. ↑: promotion; ↓: inhibition.