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. 2021 Dec 23;12:788524. doi: 10.3389/fphar.2021.788524

TABLE 1.

Demographics, medical comorbidities, and pain characteristics, by population and by pain subgroup.

All patients; n (%) Postsurgical pain; n (%) Post-traumatic pain; n (%) Migraine-like pain; n (%) Unilateral pain; n (%)
101 (100%) 27 (26.7%) 17 (16.8%) 41 (40.6%) 16 (15.8%)
Demographics
 Age (mean, SD; years) 55 (17) 54 (18) 53 (18) 52 (17) 61 (15)
 Gender, female 65 (64.4%) 17 (63.0%) 14 (82.4%) 25 (61.0%) 9 (56.3%)
 Race, White 93 (92.1%) 24 (88.9%) 16 (88.9%) 39 (95.1%) 14 (87.5%)
 Ethnicity, Hispanic 31 (30.7%) 8 (29.6%) 5 (29.1%) 11 (26.8%) 7 (43.8%)
Medical Comorbidities
 Chronic joint pain 28 (27.7%) 1 (3.7%) 7 (41.2%) 15 (36.6%) 5 (31.3%)
 Fibromyalgia 8 (7.9%) 2 (7.4%) 0 (0) 4 (9.8%) 2 (12.5%)
 Migraine 25 (24.8%) 6 (22.2%) 2 (11.8%) 16 (39.0%) 1 (6.3%)
 Peripheral neuropathy 4 (4.0%) 3 (11.1%) 0 (0) 0 (0) 1 (6.3%)
 Trigeminal neuralgia 7 (6.9%) 2 (7.4%) 0 (0) 2 (4.9%) 3 (18.8%)
 Herpetic neuralgia 5 (5.0%) 0 (0) 2 (11.8%) 2 (4.9%) 1 (6.3%)
Ocular History
 Pain >1 year 93 (92.1%) 24 (88.9%) 17 (100%) 38 (92.7%) 14 (87.5%)
 Post-LASIK 9 (8.9%) 9 (33.3%) 0 (0) 0 (0) 0 (0)
 Post-PRK 2 (2.0%) 2 (7.4%) 0 (0) 0 (0) 0 (0)
 Post-CE/iol 5 (4.9%) 5 (19.0%) 0 (0) 0 (0) 0 (0)
Pain Triggers and Descriptors
 Photophobia 50 (49.5%) 11 (40.7%) 3 (17.6%) 36 (87.8%) 0 (0)
 Cutaneous Allodynia a 20 (19.8%) 4 (14.8%) 7 (41.2%) 7 (17.1%) 2 (12.5%)
 Paresthesia (tingling) 9 (8.9%) 2 (7.4%) 0 (0) 6 (14.6%) 1 (6.3%)
 Foreign Body Sensation 10 (9.9%) 3 (11.1%) 4 (23.5%) 2 (4.9%) 1 (6.3%)
 Dull pain 4 (4.0%) 0 (0) 2 (11.8%) 1 (2.4%) 1 (6.3%)
 Throbbing/Shooting pain 20 (19.8%) 7 (25.9%) 1 (5.8%) 9 (22%) 3 (18.8%)
a

Pain on light touch of the skin around the eye.

SD = standard deviation; LASIK = laser-assisted in situ keratomileusis; PRK = photorefractive keratectomy; CE/iol = cataract extraction and intraocular lens.