TABLE 4.

Optimal pathway analysis for time to diagnosis (years) and mean total costs pre‐diagnosis (£)

Estimation method	Mean time to diagnosis	Mean total costs pre‐diagnosis
Raw data	2.74 years (SE = 0.44)	£8607 (SE = 1079.86)
GLM	2.74 years (SE = 0.38)	£ 8927 (SE = 1020.31)
GLM‐based optimal	1.01 years (SE = 0.11)	£4193 (SE = 393.52)
GLM‐based savings	1.74 years (SE = 0 .34)	£4734 (SE = 896.68)
Bootstrap + OLS (simulation)	2.73 (SD = 0.43)	£8619 (SD = 1054.82)
Simulation‐based optimal	1.07 (SD = 0.25)	£5533 (SD = 1383.06)
Simulation‐based savings	1.65 (SD = 0.38)	£3087 (SD = 961.82)

Abbreviations: GLM, generalized linear modeling; OLS, ordinary least squares.