Dhillon 2012.
Study name | Cognitive rehabilitation for breast cancer survivors with perceived cognitive impairment |
Methods | RCT |
Participants |
Inclusion criteria At least 18 years of age with an invasive breast cancer diagnosis, surgery completed within 5 years and completion of at least 3 cycles of chemotherapy 6 months previously (also radiotherapy completed 6 months previously), self‐reported cognitive function using the EORTC‐CF subscale, current use of hormonal therapies is permitted and English‐language fluency. Exclusion criteria ECOG status of more than 2, metastatic disease, major pre‐existing neurological, psychiatric condition, co‐morbidity that would interfere with cognitive testing, previous cancer (with the exception of non‐melanoma skin cancer) and prior chemotherapy receipt. Country: Australia |
Interventions |
Intervention one Definition: Computerised cognitive training (Attention Process Training) Materials: Computer programme, computer Duration: 2‐hour weekly sessions for 6 weeks Setting: Group Intervention two Definition: Compensatory strategy training Materials: None reported Duration: 2‐hour weekly sessions for 6 weeks Setting: Group Comparator: Wait‐list control |
Outcomes | Measured at baseline, 4 weeks‐, 6 months, and 12 months later Primary outcome Self‐reported cognitive function (FACT‐Cog cognitive impairment subscale) Secondary outcomes Neuropsychological test battery (WRAT reading tests, COWAT, Thurstone WFT, Category animal fluency, Trail Making Test A and B, WCST, Stroop test, WAIS digit symbol and digit span tests, Letter Number Sequence, Spatial span, HVLT, BVMT, Grooved pegboard, Cogstate Neuropsychological Test, Functional Impact Assessment) QoL: FACT‐G Anxiety/depression: HADS Fatigue: FACT‐F |
Starting date | Not yet recruiting |
Contact information | Haryana Dhillion: haryana.dhillon@sydney.edu.au |
Notes |