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. 2016 Aug 16;2016(8):CD011325. doi: 10.1002/14651858.CD011325.pub2

Dhillon 2012.

Study name Cognitive rehabilitation for breast cancer survivors with perceived cognitive impairment
Methods RCT
Participants Inclusion criteria
At least 18 years of age with an invasive breast cancer diagnosis, surgery completed within 5 years and completion of at least 3 cycles of chemotherapy 6 months previously (also radiotherapy completed 6 months previously), self‐reported cognitive function using the EORTC‐CF subscale, current use of hormonal therapies is permitted and English‐language fluency.
Exclusion criteria
ECOG status of more than 2, metastatic disease, major pre‐existing neurological, psychiatric condition, co‐morbidity that would interfere with cognitive testing, previous cancer (with the exception of non‐melanoma skin cancer) and prior chemotherapy receipt.
Country: Australia
Interventions Intervention one
Definition: Computerised cognitive training (Attention Process Training)
Materials: Computer programme, computer
Duration: 2‐hour weekly sessions for 6 weeks
Setting: Group
Intervention two
Definition: Compensatory strategy training
Materials: None reported
Duration: 2‐hour weekly sessions for 6 weeks
Setting: Group
Comparator: Wait‐list control
Outcomes Measured at baseline, 4 weeks‐, 6 months, and 12 months later
Primary outcome
Self‐reported cognitive function (FACT‐Cog cognitive impairment subscale)
Secondary outcomes
Neuropsychological test battery (WRAT reading tests, COWAT, Thurstone WFT, Category animal fluency, Trail Making Test A and B, WCST, Stroop test, WAIS digit symbol and digit span tests, Letter Number Sequence, Spatial span, HVLT, BVMT, Grooved pegboard, Cogstate Neuropsychological Test, Functional Impact Assessment)
QoL: FACT‐G
Anxiety/depression: HADS
Fatigue: FACT‐F
Starting date Not yet recruiting
Contact information Haryana Dhillion: haryana.dhillon@sydney.edu.au
Notes