Matthews 2007.

Study name	The Activity Intervention for Chemobrain (TACTIC)
Methods	RCT
Participants	Inclusion criteria Aged 18 years or older with non‐metastatic cancer who has received at least 4 cycles of chemotherapy and report persistent cognitive difficulties following treatment. Exclusion criteria Have no prior diagnosis of CNS cancer, not have engaged in regular exercise (more than 20 minutes a day, more than 5 days a week for at least 3 months), no cardiovascular disease or orthopaedic problems and no major systemic diseases (e.g. liver). Country: USA
Interventions	Definition: Aerobic exercise Materials: none reported Duration: 6 months Setting: none reported Comparator: 6 compensatory strategies to aid memory and cognition
Outcomes	Reported details indicate that trial is a cross‐sectional study with follow‐up 6 months later at end of intervention Primary outcome Objective cognitive function using a neuropsychological test battery Secondary outcome(s) Psychological status, cardiorespiratory fitness and inflammatory biomarkers
Starting date	Trial finished: will not share data
Contact information	Charles Matthews: matthewsce@mail.nih.gov
Notes