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. 2022 Jan 6;15:2. doi: 10.1186/s13072-021-00433-4

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Refinement of sperm H3K9me2 at gene promoters driving spermatogenesis and distal intergenic regions constrained within Lamina-Associated Domains during epididymal maturation. A Correlation analysis between H3K9me2 ChIP-seq signals derived from sperm isolated from the caput and cauda regions of the epididymis (n = 2). Venn diagrams comparing changes in B broad and C narrow peaks between caput and cauda-derived sperm. D Integrative Genome Viewer tracks of chromosomal regions exhibiting differential H3K9me2 enrichment between caput and cauda-derived sperm. Bar chart representation of the distribution of H3K9me2 across key genomic features between E caput and F cauda-derived samples. Heatmaps displaying the enrichment of H3K9me2 signals across G CpG islands, H regions exhibiting a signature of distal enhancers, or I Lamina-Associated Domains