Figure 3.

Left: Box showing both numbers and percentage of participants who showed a CD4⁺ or/and CD8⁺ T-cell response. Middle and right graphs: percentage of CD4⁺, CD8⁺/IFN-γ⁺ T-cells in the responders to VIDAS TB-IGRA AG. Each dot/square represents a single active TB or LTBI patient, black lines represent median values. Individuals who showed both CD4⁺ and CD8⁺ responses are represented with the same colour in all graphs. Individuals who showed a single CD4⁺ or CD8⁺ T-cell response are indicated in white. No differences between groups were observed using the Mann–Whitney test. AG = (VIDAS TB-IGRA) antigen tube reagent; LTBI = latent TB infection; IFN-γ = interferon-gamma.