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. 2022 Jan 6;23:18. doi: 10.1186/s12859-021-04532-7

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Run time of the tested programs for 481 alignments of 5 sequences each from the BRAliBase 2.1 benchmark, including the SRP data. The calculation of the base pair probabilities is included in the run time. For RNAmountAlign we multiplied the time for computing 384 alignments that do not contain wildcards with factor $\frac{481}{384}$ in order to compare it with the other tools